Description

Magainin G CAS NO 117682-76-5 is a synthetic antimicrobial peptide (AMP) derived from the natural defense mechanisms of the African clawed frog. This compound is valued for its broad-spectrum activity against bacteria, fungi, and certain viruses, making it a significant molecule for research into novel therapeutic agents. It is primarily sought by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for applications in antimicrobial drug discovery, biomaterials, and studying host defense peptides.

Application

• Antimicrobial Research & Drug Discovery: As a model peptide for studying the structure-activity relationships of host defense peptides and developing new antibiotic candidates.
• Biomaterial Coatings: Incorporation into medical device coatings, wound dressings, or implant surfaces to impart antimicrobial properties and prevent biofilm formation.
• Life Science Reagents: Used as a biochemical tool in laboratory studies to investigate bacterial membrane interactions, mechanisms of antimicrobial action, and immune modulation.
• Cosmeceutical Research: Exploration in topical formulations for its potential preservative or skin-conditioning benefits, leveraging its natural origin and antimicrobial profile.
• Veterinary Pharmaceutical Development: Research into applications for treating infections in animals, given its origin from an amphibian source.

Basic Information

Product Name	Magainin G
CAS No.	117682-76-5
Molecular Formula	C106H169N31O26S
Molecular Weight	~2293.8 g/mol
Synonyms	Magainin G; Magainin-G; Pexiganan precursor; Antimicrobial peptide G; GIGKFLHSAKKFGKAFVGEIMNS; Iseganan precursor; MSI-78A; Synthetic Magainin G Peptide
EINECS	Contact for details

Quality Control

Our Magainin G is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for critical research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, identity, and other relevant specifications is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical values (±10%)
Single-Chain Proportion (HPLC)	≥ 90%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.