Description

Magainin A is a naturally occurring antimicrobial peptide (AMP) isolated from the skin of the African clawed frog, *Xenopus laevis*. This compound represents a significant class of host-defense peptides with broad-spectrum activity against bacteria, fungi, and certain viruses. It is of primary interest to researchers and developers in the pharmaceutical, biotechnology, and life science sectors for its potential in novel therapeutic development, antimicrobial coatings, and as a model compound for studying peptide-membrane interactions.

Application

• Antimicrobial Agent Research: Fundamental and applied research into novel antibiotics and antifungal agents to combat drug-resistant pathogens.
• Biomedical Material Development: Incorporation into medical device coatings, wound dressings, and implant surfaces to prevent biofilm formation and infection.
• Cosmeceutical Formulations: Exploration in skincare products for its potential preservative and anti-inflammatory properties.
• Veterinary Pharmaceutical Development: Research for topical or systemic treatments in animal health.
• Biochemical & Biophysical Studies: Used as a standard or tool peptide in studies of peptide structure, function, and mechanism of action on lipid bilayers.
• Food Safety Applications: Investigation as a natural preservative for food packaging or surface sanitization.

Basic Information

Product Name	Magainin A
CAS No.	117665-47-1
Molecular Formula	C106H168N32O26S
Molecular Weight	~2400.8 g/mol
Synonyms	Magainin 1; Magainin I; PGS; Preprocaerulein Fragment 59-92; Xenopsin Precursor Fragment; Gly-Leu-Gly-Ser-Leu-Phe-Lys-Lys-Val-Leu-Gly-Lys-Phe-Ile-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser; GIGKFLHSAKKFGKAFVGEIMNS
EINECS	Contact for details

Quality Control

Our Magainin A is produced and handled under strict quality protocols suitable for research and development. Each batch is characterized to ensure identity, purity, and biological activity. A comprehensive Certificate of Analysis (COA) is provided, detailing results from HPLC for purity, Mass Spectrometry (MS) for confirmation, and Amino Acid Analysis (AAA). We adhere to relevant quality management standards to ensure batch-to-batch consistency and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into single-use quantities to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Solubility	Soluble in water, dilute acetic acid
Single Impurity (HPLC)	≤ 1.0%
Endotoxin Level	< 10 EU/mg (where specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.