Description

Benzyloxycarbonyl-Leucyl-Methionine-H CAS NO 117611-43-5 is a protected dipeptide derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive intermediate for the controlled construction of complex peptide chains and other bioactive molecules. This compound is essential for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on peptide-based drug discovery and process development.

Application

• Peptide Synthesis Intermediate: A key protected fragment in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Used in the R&D of novel therapeutic peptides and peptidomimetics.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides for studying enzyme mechanisms and protein-protein interactions.
• Fine Chemical Production: Serves as a chiral synthon for the asymmetric synthesis of non-peptide compounds.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Benzyloxycarbonyl-Leucyl-Methionine-H
CAS No.	117611-43-5
Molecular Formula	C20H30N2O5S
Molecular Weight	410.53 g/mol
Synonyms	Z-Leu-Met-OH; Cbz-Leu-Met-OH; N-Carbobenzoxy-L-leucyl-L-methionine; Benzyl N-[(2S)-1-[[(2S)-2-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate; Nα-Cbz-L-leucyl-L-methionine; L-Methionine, N-[(phenylmethoxy)carbonyl]-L-leucyl-; Z-L-Leu-L-Met-OH
EINECS	Contact for details

Quality Control

Our Benzyloxycarbonyl-Leucyl-Methionine-H is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.