Description

3-Mercaptopropionyl-Tyr-D-Trp-Lys-Val-Cys-Phe-Nh2, (Disulfide Bond Between Deamino-Cys1 And Cys6) is a synthetic peptide analog of somatostatin, featuring a critical intramolecular disulfide bridge that stabilizes its bioactive conformation. This compound is of significant interest for its potent biological activity and high binding affinity to somatostatin receptors. It serves as a crucial research-grade biochemical and a potential precursor in the development of novel therapeutic agents, primarily targeting the pharmaceutical and biotechnology research sectors.

Application

• Pharmaceutical Research & Development: As a reference standard and active compound in the study of somatostatin receptor (SSTR) biology, signal transduction, and metabolic regulation.
• Drug Discovery Programs: Utilized as a lead compound or molecular scaffold for designing new peptide-based therapeutics targeting neuroendocrine tumors, acromegaly, and other hormone-related disorders.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays, receptor binding studies, and competitive inhibition tests.
• Academic & Clinical Research: Used in university and institutional labs to investigate peptide structure-activity relationships (SAR), hormone secretion mechanisms, and potential diagnostic applications.
• Preclinical Studies: Serves as a key material in animal model studies to evaluate pharmacokinetics, biodistribution, and efficacy of somatostatin analogs.

Basic Information

Product Name	3-Mercaptopropionyl-Tyr-D-Trp-Lys-Val-Cys-Phe-Nh2, (Disulfide Bond Between Deamino-Cys1 And Cys6)
CAS No.	117580-24-2
Molecular Formula	C52H70N12O11S2
Molecular Weight	1095.3 g/mol
Synonyms	Deamino-Cys1, Cys6 Somatostatin-14; [Deamino-Cys1, Cys6]-Somatostatin-14; 3-Mercaptopropionyl-Somatostatin-14 (cyclic 1-6 disulfide); SRIF-14 analog; Somatostatin (1-14) (human, rat) cyclic (1-6) disulfide derivative; BIM-23014 (related analog); SSTR agonist peptide; Cyclic somatostatin peptide fragment.
EINECS	Contact for details

Quality Control

This peptide is manufactured under strict cGMP-like conditions to ensure batch-to-batch consistency and high purity suitable for research applications. Quality is verified through a comprehensive suite of analytical techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each batch to support regulatory submissions and ensure research integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.