Description

n-Methyl-D-Asparagine is a specialized, non-proteinogenic amino acid derivative of D-asparagine, featuring a methyl group substitution on the nitrogen atom. This modification imparts unique biochemical properties, making it a valuable chiral building block and research chemical for advanced life science applications. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in peptide synthesis, metabolic pathway studies, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of peptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used as a substrate or analog in enzymatic studies, particularly those involving asparagine metabolism or methyltransferase activity.
• Peptide Synthesis: Employed as a modified amino acid residue in solid-phase or solution-phase peptide synthesis to alter peptide stability, bioavailability, or receptor binding.
• Neuroscience Studies: Investigated for its potential interactions with neurotransmitter systems, given its structural similarity to endogenous amino acids.
• Reference Standard: Used as a high-purity analytical standard in chromatography (HPLC, LC-MS) for method development and quality control in related compound analysis.
• Metabolite Synthesis: A precursor in the chemical synthesis of complex natural products or specific metabolites for diagnostic and research purposes.

Basic Information

Product Name	n-Methyl-D-Asparagine
CAS No.	117414-80-9
Molecular Formula	C5H10N2O3
Molecular Weight	146.15 g/mol
Synonyms	N-Methyl-D-asparagine; (R)-2-Amino-3-(methylamino)-3-oxopropanoic acid; D-N-Methylasparagine; Methyl-D-asparagine; (2R)-2-Amino-3-(methylcarbamoyl)propanoic acid; D-α-Amino-N-methylsuccinamic acid; Nω-Methyl-D-asparagine
EINECS	Contact for details

Quality Control

Our n-Methyl-D-Asparagine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.