Description

Ozagrel-009-E CAS NO 117390-06-4 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) primarily used in the synthesis of antiplatelet and antithrombotic medications. Its significance lies in its role as a key building block for developing therapeutic agents that target thromboxane A2 synthase, a crucial enzyme in platelet aggregation pathways. This compound is essential for pharmaceutical manufacturers and research institutions focused on cardiovascular drug development, anticoagulant therapies, and advanced biochemical research.

Application

• Pharmaceutical API Synthesis: A critical intermediate in the commercial production of Ozagrel and related antiplatelet drugs.
• Cardiovascular Research: Used in biochemical and pharmacological studies targeting thromboxane A2 synthase inhibition for stroke and thrombosis prevention.
• Fine Chemical Manufacturing: Serves as a precursor for other specialized, high-value pharmaceutical compounds.
• Reference Standard: Employed as an analytical standard in quality control (QC) and quality assurance (QA) laboratories for method development and validation.
• Academic & Institutional Research: Utilized in universities and research institutes for investigating platelet aggregation mechanisms and developing new therapeutic candidates.

Basic Information

Product Name	Ozagrel-009-E
CAS No.	117390-06-4
Molecular Formula	C13H12N2O2
Molecular Weight	228.25 g/mol
Synonyms	(E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic Acid; Ozagrel; (E)-Ozagrel; OKY-046; (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]prop-2-enoic Acid; cis-Ozagrel Impurity; Thromboxane A2 Synthase Inhibitor
EINECS	Contact for details

Quality Control

Our Ozagrel-009-E is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent control of residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available upon request, ensuring compliance with cGMP and relevant pharmaceutical intermediate specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.