Description

3-Pyroglutamylthiazolidine-4-Carboxylic Acid is a specialized heterocyclic compound that serves as a key intermediate in advanced organic synthesis. Its unique molecular structure, featuring fused pyroglutamyl and thiazolidine moieties, makes it a valuable precursor for the development of novel pharmaceutical agents and bioactive molecules. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Peptidomimetic Research: Used in the design and development of peptidomimetics and constrained peptides due to its rigid, bicyclic structure.
• Bioconjugation Chemistry: Serves as a versatile linker or spacer molecule in the conjugation of peptides, proteins, or other biomolecules.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and protein-protein interactions.
• Cosmeceutical Ingredient Synthesis: A precursor in the manufacturing of advanced active ingredients for high-end skincare formulations.
• Academic & Industrial R&D: Essential for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	3-Pyroglutamylthiazolidine-4-Carboxylic Acid
CAS No.	117241-40-4
Molecular Formula	C9H12N2O4S
Molecular Weight	244.27 g/mol
Synonyms	L-2-(2-Oxopyrrolidin-5-yl)-1,3-thiazolidine-4-carboxylic Acid; (4R)-2-[(5S)-5-Oxo-L-prolyl]-1,3-thiazolidine-4-carboxylic Acid; 5-Oxo-L-prolylthiazolidine-4-carboxylic Acid; PTCA; 3-(5-Oxoprolyl)thiazolidine-4-carboxylic Acid; L-Pyroglutamyl-L-thiazolidine-4-carboxylic Acid; NSC 339587
EINECS	Contact for details

Quality Control

Our 3-Pyroglutamylthiazolidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.