Description

2-Methyl-4-Carboxy-5-Hydroxy-3,4,5,6-Tetrahydropyrimidine is a high-purity, functionalized tetrahydropyrimidine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both carboxylic acid and hydroxyl groups on a saturated pyrimidine ring, makes it an invaluable intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, or plant growth regulators where its heterocyclic core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in metal-organic frameworks (MOFs) or homogeneous catalysis due to its multiple coordination sites.
• Fine Chemical Production: Employed in the multistep synthesis of complex dyes, pigments, or other performance chemicals requiring a functionalized heterocyclic scaffold.
• Biochemical Research: Potentially used as a substrate analog or inhibitor in enzymatic studies related to nucleotide metabolism.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal or mechanical properties.

Basic Information

Product Name	2-Methyl-4-Carboxy-5-Hydroxy-3,4,5,6-Tetrahydropyrimidine
CAS No.	117229-60-4
Molecular Formula	C7H10N2O3
Molecular Weight	170.17 g/mol
Synonyms	5-Hydroxy-2-methyl-3,4,5,6-tetrahydro-4-pyrimidinecarboxylic acid; 2-Methyl-4,5-dihydroxypyrimidine-4-carboxylic acid (tautomeric form); 4-Carboxy-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine; 2-Methyl-4-carboxy-5-hydroxytetrahydropyrimidine; Tetrahydro-2-methyl-4-carboxy-5-hydroxypyrimidine; 2-Methyl-4,5-dihydroxypyrimidine-4-carboxylate; 2-Methyl-4,5-dihydroxypyrimidine-4-carboxylic acid (tautomer); 2-Methyl-4-carboxy-5-hydroxy-3,4,5,6-tetrahydro-2H-pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-Carboxy-5-Hydroxy-3,4,5,6-Tetrahydropyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.