Description

Tyrosyl-Arginyl-Glycyl-Phenylalanine Ethyl Ester is a synthetic tetrapeptide derivative, specifically the ethyl ester of the YRGF sequence. This compound serves as a crucial advanced intermediate in pharmaceutical research and peptide synthesis. It is primarily utilized by R&D scientists and manufacturers in the biotechnology, pharmaceutical, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of longer, more complex peptide-based drug candidates.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly for proteases and peptidases.
• Peptide Library Construction: A valuable component in combinatorial chemistry for generating diverse peptide libraries for screening.
• Cosmeceutical Development: Investigated for potential use in advanced skincare formulations targeting specific biological pathways.
• Academic Research: Serves as a model compound in studies of peptide stability, delivery, and structure-activity relationships (SAR).

Basic Information

Product Name	Tyrosyl-Arginyl-Glycyl-Phenylalanine Ethyl Ester
CAS No.	117062-52-9
Molecular Formula	C33H47N9O8
Molecular Weight	697.79 g/mol
Synonyms	YRGF-OEt; Tyr-Arg-Gly-Phe-OEt; YRGF Ethyl Ester; H-Tyr-Arg-Gly-Phe-OEt; Tetrapeptide YRGF Ethyl Ester; L-Tyrosyl-L-arginyl-glycyl-L-phenylalanine ethyl ester; N-(N-(N-(N-L-Tyrosyl-L-arginyl)glycyl)-L-phenylalanine) ethyl ester
EINECS	Contact for details

Quality Control

Our Tyrosyl-Arginyl-Glycyl-Phenylalanine Ethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and cGMP-grade standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.