Description

Atriopeptin Analog I is a synthetic peptide analog designed for research and development purposes. This compound is of significant interest for its role in studying cardiovascular and renal physiology, particularly in relation to natriuretic peptide pathways. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in preclinical studies and biochemical assay development.

Application

• Biochemical Research: Used as a reference standard or active agent in studies investigating natriuretic peptide receptors (NPR-A, NPR-B) and their signaling cascades.
• Cardiovascular Pharmacology: Employed in preclinical models to explore potential therapeutic effects on blood pressure regulation, vasodilation, and heart failure.
• Renal Function Studies: Applied in research focused on diuresis, natriuresis, and the modulation of electrolyte and water balance.
• Assay Development: Serves as a critical component in the development and validation of high-throughput screening (HTS) assays and ELISA tests targeting the natriuretic peptide system.
• Peptide Chemistry Reference: Used as a building block or intermediate in the synthesis of more complex peptide structures for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Atriopeptin Analog I
CAS No.	117038-68-3
Molecular Formula	C45H69N13O12S2
Molecular Weight	1032.2 g/mol
Synonyms	Atriopeptin I Analog; ANP (5-28), Cys(7)-Cys(28)-amide (human); Atrial Natriuretic Peptide (5-28) amide, [Cys7,Cys28]-; hANP (5-28), cyclic; [Cys7, Cys28]-ANP (5-28) amide; Atriopeptin-28 (cyclic); cANF (4-28); Cyclic Atrial Natriuretic Factor (4-28)
EINECS	Contact for details

Quality Control

Our Atriopeptin Analog I is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.