Description

H-Lys-D-Pro-Thr-Oh is a synthetic tripeptide derivative with the CAS registry number 117027-34-6. This compound is a crucial building block in advanced pharmaceutical research and development, particularly for the synthesis of novel peptide-based therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of diagnostic agents. The specific stereochemistry and sequence make it a valuable intermediate for creating targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of complex peptide drugs and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used as a building block in combinatorial chemistry and high-throughput screening for identifying new therapeutic candidates.
• Medicinal Chemistry: Serves as a core structure for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties.
• Bioconjugation: Can be utilized in the development of peptide-drug conjugates (PDCs) and other targeted delivery systems.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and proteomics research.
• Diagnostic Agent Development: Potential use in the synthesis of peptide-based imaging probes and diagnostic markers.

Basic Information

Product Name	H-Lys-D-Pro-Thr-Oh
CAS No.	117027-34-6
Molecular Formula	C14H26N4O5
Molecular Weight	330.38 g/mol
Synonyms	Lysyl-D-prolyl-threonine; H-Lys-D-Pro-Thr-OH; (2S)-2-[[(2S)-6-Amino-2-[[(2R)-pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-3-hydroxybutanoic acid; L-Lysyl-D-prolyl-L-threonine; Tripeptide Lys-D-Pro-Thr; 117027-34-6; Lys-D-Pro-Thr
EINECS	Contact for details

Quality Control

Our H-Lys-D-Pro-Thr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.