Description

[1,1'-Biphenyl]-4-Ol, 4'-Bromo-2'-Fluoro- CAS NO 116831-27-7 is a high-purity, halogenated biphenyl derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise molecular structure, which enables the construction of complex molecules for high-value applications. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the halogenated biphenyl core.
• Liquid Crystal & OLED Materials: Serves as a precursor for the development of specialty chemicals used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the creation of high-performance polymers with specific thermal or optical properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Specialty Dyes & Pigments: Utilized in the synthesis of complex dye molecules where the biphenyl structure provides stability and color properties.

Basic Information

Product Name	[1,1'-Biphenyl]-4-Ol, 4'-Bromo-2'-Fluoro-
CAS No.	116831-27-7
Molecular Formula	C12H8BrFO
Molecular Weight	267.10 g/mol
Synonyms	4'-Bromo-2'-fluoro-[1,1'-biphenyl]-4-ol; 4'-Bromo-2'-fluoro-4-hydroxybiphenyl; 2-Fluoro-4'-bromobiphenyl-4-ol; 4-(4-Bromo-2-fluorophenyl)phenol; 4-Hydroxy-4'-bromo-2'-fluorobiphenyl; Biphenyl-4-ol, 4'-bromo-2'-fluoro-; 116831-27-7
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-4-Ol, 4'-Bromo-2'-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.