Description

Tryptophyl-Leucyl-Glutamic Acid is a synthetic tripeptide composed of the amino acids tryptophan, leucine, and glutamic acid. This compound is of significant interest in biochemical and pharmaceutical research for its role as a potential bioactive peptide or a key intermediate in peptide synthesis. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in drug discovery, proteomics, and as a building block for more complex polypeptides.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and metabolic pathway analysis.
• Pharmaceutical Intermediates: Serves as a crucial building block for the synthesis of longer, therapeutically relevant peptide chains.
• Proteomics & Peptide Mapping: Employed in mass spectrometry and chromatography for method development and calibration.
• Cell Culture & Media Supplements: Investigated for potential use as a specialized nutrient or signaling molecule in advanced cell culture systems.
• Cosmeceutical Peptide Synthesis: Acts as a precursor in the development of bioactive peptides for skincare formulations.
• Academic & Industrial R&D: Fundamental tool for studying peptide structure, function, and stability in various chemical environments.

Basic Information

Product Name	Tryptophyl-Leucyl-Glutamic Acid
CAS No.	116778-82-6
Molecular Formula	C₂₁H₂₈N₄O₇
Molecular Weight	448.47 g/mol
Synonyms	Trp-Leu-Glu; WLE; Tryptophan-Leucine-Glutamic Acid; H-Trp-Leu-Glu-OH; L-Tryptophyl-L-leucyl-L-glutamic acid; (S)-2-((S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-4-methylpentanamido)pentanedioic acid; Tryptophanylleucylglutamic acid
EINECS	Contact for details

Quality Control

Our Tryptophyl-Leucyl-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide a Certificate of Analysis (COA) with each shipment, detailing all relevant specifications to ensure it meets the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.