Description

Naltrexamine, N(Beta)-(Leu-Arg-Arg-Leu-Phe)- CAS NO 116764-29-5 is a specialized synthetic peptide derivative, structurally related to opioid antagonists. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of receptor binding and signal transduction pathways. It serves as a critical intermediate or reference standard for researchers and manufacturers in the fields of neuropharmacology, peptide chemistry, and drug discovery.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and study of novel opioid receptor antagonists and related therapeutic agents.
• Biochemical Research: Employed in receptor binding assays and studies investigating the structure-activity relationships (SAR) of peptide-based compounds targeting neurological pathways.
• Drug Discovery Programs: Serves as a building block or a pharmacological tool compound in high-throughput screening and lead optimization processes.
• Academic Research: Utilized in university and institutional labs for fundamental studies in neurochemistry, peptide biology, and medicinal chemistry.
• Reference Standard Manufacturing: Supplied to analytical laboratories and quality control departments for use as a certified reference material (CRM) to ensure analytical method accuracy.

Basic Information

Product Name	Naltrexamine, N(Beta)-(Leu-Arg-Arg-Leu-Phe)- CAS NO 116764-29-5
CAS No.	116764-29-5
Molecular Formula	C46H75N15O9
Molecular Weight	966.2 g/mol
Synonyms	Naltrexamine, N(β)-(Leu-Arg-Arg-Leu-Phe)-; N(β)-(Leu-Arg-Arg-Leu-Phe)naltrexamine; Naltrexamine LRRLLF conjugate; Naltrexamine pentapeptide derivative; N-(β-(Leu-Arg-Arg-Leu-Phe))naltrexamine; Opioid antagonist peptide conjugate; Naltrexamine-Leu-Arg-Arg-Leu-Phe; LRRLLF-Naltrexamine
EINECS	Contact for details

Quality Control

Our Naltrexamine, N(Beta)-(Leu-Arg-Arg-Leu-Phe)- CAS NO 116764-29-5 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We can support development projects requiring compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); containers should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. Store in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.