Description

3-(3-Fluorophenoxy)Propan-1-Amine is a versatile fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and phenoxy linker impart desirable biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine moiety enhances bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for their unique electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-(3-Fluorophenoxy)Propan-1-Amine
CAS No.	116753-49-2
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	3-(3-Fluorophenoxy)propylamine; 1-Amino-3-(3-fluorophenoxy)propane; 3-(3-Fluorophenoxy)-1-propanamine; 3-Fluorophenoxypropylamine; γ-(3-Fluorophenoxy)propylamine; 3-Fluoro-ω-aminophenoxypropane; 116753-49-2; 3-(3-Fluorophenoxy)propanamine
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenoxy)Propan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.