Description

Fmoc-Ala-Gly-Oh CAS NO 116747-54-7 is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for the controlled and efficient assembly of complex peptide sequences, offering high coupling efficiency and minimal racemization. It is a critical raw material for researchers and manufacturers in pharmaceutical development, biotechnology, and proteomics who require high-purity intermediates for peptide-based drug discovery and production.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the sequential assembly of custom peptide sequences in automated synthesizers.
• Pharmaceutical Intermediates: Used in the research and development of therapeutic peptides, including hormone analogs and antimicrobial peptides.
• Bioconjugation: Serves as a linker or spacer molecule in the creation of peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify novel bioactive peptide leads.
• Academic & Industrial Research: A standard reagent for studying peptide structure, function, and stability in biochemistry and molecular biology labs.
• Production of Custom Peptides: Used by CROs and CDMOs for the contract manufacturing of peptides for clinical and commercial applications.

Basic Information

Product Name	Fmoc-Ala-Gly-Oh
CAS No.	116747-54-7
Molecular Formula	C₂₁H₂₂N₂O₅
Molecular Weight	382.41 g/mol
Synonyms	Fmoc-L-Ala-Gly-OH; Fmoc-Ala-Gly; N-(9-Fluorenylmethoxycarbonyl)-L-alanylglycine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanylglycine; Fmoc-L-alanyl-glycine; Fmoc-Ala-Gly-OH; Fmoc-Ala-Gly dipeptide; N-Fmoc-L-alanylglycine
EINECS	Contact for details

Quality Control

Our Fmoc-Ala-Gly-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-20.0° to -24.0° (c=1, DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.