Description

Phenol, 3,5-Difluoro-4-(Trifluoromethyl)- CAS NO 116640-11-0 is a highly fluorinated phenol derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts significant lipophilicity, metabolic stability, and electronic properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced performance. It serves as a critical intermediate for creating complex molecules where these specific fluorine patterns are required.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer Modification: Employed to introduce fluorine-containing phenolic groups into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Electronic Materials: Acts as a key synthon in the development of materials for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research exploring structure-activity relationships (SAR) influenced by polyfluorination.

Basic Information

Product Name	Phenol, 3,5-Difluoro-4-(Trifluoromethyl)-
CAS No.	116640-11-0
Molecular Formula	C7H3F5O
Molecular Weight	198.09 g/mol
Synonyms	4-(Trifluoromethyl)-3,5-difluorophenol; 3,5-Difluoro-4-(trifluoromethyl)phenol; 2,6-Difluoro-4-(trifluoromethyl)phenol; 4-Hydroxy-2,6-bis(fluoranyl)-1-(trifluoromethyl)benzene; Phenol, 3,5-difluoro-4-(trifluoromethyl)-; 1-Hydroxy-3,5-difluoro-4-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our Phenol, 3,5-Difluoro-4-(Trifluoromethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizers, strong bases, and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.