Description

D-Norleucine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester is a protected amino acid derivative, specifically the methyl ester of Boc-D-Norleucine. This compound is a crucial chiral building block in organic synthesis, valued for its role in constructing complex peptide structures with high stereochemical purity. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of novel therapeutics, peptide-based drugs, and bioactive compounds.

Application

• Peptide Synthesis: A key chiral intermediate for the solid-phase and solution-phase synthesis of custom peptides and peptidomimetics.
• Pharmaceutical Research: Used in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease studies.
• Bioconjugation: Serves as a modified amino acid for creating labeled peptides or protein conjugates for diagnostic and research applications.
• Chemical Biology: Employed in the synthesis of probe molecules and inhibitors to study enzyme function and protein-protein interactions.
• Agrochemical Development: Acts as a precursor in the synthesis of specialized amino acid-based compounds for crop protection research.

Basic Information

Product Name	D-Norleucine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester
CAS No.	116611-59-7
Molecular Formula	C12H23NO4
Molecular Weight	245.32 g/mol
Synonyms	Boc-D-Norleucine-OMe; (R)-2-((tert-Butoxycarbonyl)amino)hexanoic acid methyl ester; Methyl (R)-2-((tert-butoxycarbonyl)amino)hexanoate; Boc-D-Nle-OMe; Boc-D-2-Aminohexanoic acid methyl ester; D-Norleucine, N-BOC-, methyl ester; Methyl N-Boc-D-norleucinate
EINECS	Contact for details

Quality Control

Our Boc-D-Norleucine-OMe is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.