Description

Sarafotoxin 6C, [Lys4]- is a synthetic peptide analog of the potent vasoconstrictor sarafotoxin, specifically modified at the fourth position with a lysine residue. This compound is a crucial research tool for investigating endothelin receptor subtypes, particularly ETB receptors, due to its selective agonist activity. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in cardiovascular research, drug discovery, and signal transduction pathway studies.

Application

• Endothelin Receptor Research: Selective agonist for the pharmacological characterization and study of ETB receptor subtypes in vitro and in vivo.
• Cardiovascular Pharmacology: Investigation of vasoconstriction, blood pressure regulation, and vascular smooth muscle cell function.
• Cell Signaling Studies: Tool for probing G-protein coupled receptor (GPCR) pathways and intracellular calcium mobilization.
• Drug Discovery & Development: Used as a reference standard and screening tool in the development of novel endothelin receptor antagonists.
• Academic & Institutional Research: Fundamental research in physiology, pharmacology, and molecular biology related to the endothelin system.

Basic Information

Product Name	Sarafotoxin 6C, [Lys4]-
CAS No.	116495-45-5
Molecular Formula	C115H174N30O33S5
Molecular Weight	2585.2 g/mol
Synonyms	[Lys4]-Sarafotoxin S6c; Sarafotoxin S6c, [Lys4]-; S6c, [Lys4]-Sarafotoxin; Endothelin ETB Receptor Agonist [Lys4]-S6c; Sarafotoxin 6c (Lys4); SRTX-6c, [Lys4]-; Selective ETB Receptor Agonist
EINECS	Contact for details

Quality Control

Our Sarafotoxin 6C, [Lys4]- is produced under stringent conditions to ensure the highest standards of purity and biological activity, suitable for critical research applications. Each batch is supported by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, peptide content, and identity are provided to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the lyophilized powder under desiccant. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to structure
Purity (HPLC)	≥95%
Peptide Content	≥80%
Water Content (KF)	≤5.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.