Description

Calcitonin, (4-Azidobenzoyl)-Arg(11,18)-Lys(14)- CAS NO 116469-30-8 is a chemically modified, bioactive peptide analog of the human calcitonin hormone. This compound is engineered for advanced biochemical research, offering a critical tool for studying bone metabolism, calcium regulation, and receptor-ligand interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic disorders and peptide-based therapeutic development.

Application

• Biochemical Research: A key reagent for in vitro and in vivo studies on calcitonin receptor activity, signaling pathways, and calcium homeostasis.
• Pharmaceutical Development: Serves as a reference standard or a lead compound in the discovery and validation of novel therapeutics for osteoporosis and Paget's disease.
• Photolabeling Studies: The 4-azidobenzoyl group enables photoaffinity labeling, making it invaluable for mapping receptor binding sites and studying protein-peptide interactions.
• Metabolic Disorder Models: Used to establish and validate experimental models related to bone resorption and calcium dysregulation.
• Peptide Chemistry & Conjugation: Acts as a specialized intermediate for further chemical modifications, conjugation, or probe development due to its reactive azido group.

Basic Information

Product Name	Calcitonin, (4-Azidobenzoyl)-Arg(11,18)-Lys(14)-
CAS No.	116469-30-8
Molecular Formula	C₁₅₀H₂₄₆N₅₀O₄₅S₂
Molecular Weight	3433.9 g/mol (approx.)
Synonyms	(4-Azidobenzoyl)-Arg(11,18)-Lys(14)-Calcitonin; 4-Azidobenzoyl-Calcitonin; Azido-Calcitonin; Photoreactive Calcitonin Analog; Calcitonin Azido Derivative; hCT analog; Photoaffinity Labeling Calcitonin
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Calcitonin, (4-Azidobenzoyl)-Arg(11,18)-Lys(14)- is characterized using advanced analytical techniques to confirm identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and other critical parameters are available upon request. We adhere to stringent quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Biological Activity	Assessed by in vitro assay (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.