Description

n-(6-Bromo-4-Hydroxypyrido[2,3-D]Pyrimidin-2-Yl)Pivalamide (Wxc05947) is a high-purity, advanced pharmaceutical intermediate belonging to the pyridopyrimidine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel small-molecule therapeutics. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new therapeutic targets.
• Biochemical Tool Compound: Serves as a reference standard or a precursor for developing biochemical probes to study specific enzyme pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures with high specificity.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	n-(6-Bromo-4-Hydroxypyrido[2,3-D]Pyrimidin-2-Yl)Pivalamide (Wxc05947)
CAS No.	116387-22-5
Molecular Formula	C₁₂H₁₃BrN₄O₂
Molecular Weight	325.16 g/mol
Synonyms	WXC-05947; Wxc05947; 2-Pivalamido-6-bromo-4-hydroxypyrido[2,3-d]pyrimidine; Pivalamide, N-(6-bromo-4-hydroxypyrido[2,3-d]pyrimidin-2-yl)-; 6-Bromo-2-(pivalamido)-4-hydroxypyrido[2,3-d]pyrimidine; 6-Bromo-4-hydroxy-2-(pivalamido)pyrido[2,3-d]pyrimidine; N-(6-Bromo-4-hydroxypyrido[2,3-d]pyrimidin-2-yl)-2,2-dimethylpropanamide
EINECS	Contact for details

Quality Control

Every batch of n-(6-Bromo-4-Hydroxypyrido[2,3-D]Pyrimidin-2-Yl)Pivalamide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.