Description

4-Bromo-3-Trifluoromethoxy-Phenylamine is a high-value halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethoxy substituents, makes it indispensable for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for functional dyes and electronic materials used in display technologies and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or functionalizing agent for creating specialty polymers with tailored thermal and chemical resistance properties.
• Cross-Coupling Reactions: An excellent substrate for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions to construct complex biaryl structures.
• Chemical Research: Employed in academic and industrial laboratories for methodological studies and the discovery of new catalytic processes.

Basic Information

Product Name	4-Bromo-3-Trifluoromethoxy-Phenylamine
CAS No.	116369-25-6
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	4-Bromo-3-(trifluoromethoxy)aniline; 3-Trifluoromethoxy-4-bromoaniline; 4-Bromo-α,α,α-trifluoro-m-anisidine; 1-Amino-4-bromo-3-(trifluoromethoxy)benzene; 4-Bromo-3-trifluoromethoxybenzenamine; Benzenamine, 4-bromo-3-(trifluoromethoxy)-; 4-Bromo-3-trifluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Trifluoromethoxy-Phenylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.