Description

4-Bromo-5-Chloro-2-Fluoroaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which enables precise molecular modifications essential for developing complex, high-performance compounds. This intermediate is primarily needed by research and development laboratories and production facilities in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for enhanced bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex, light-fast azo dyes and organic pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl structures common in many advanced materials.

Basic Information

Product Name	4-Bromo-5-Chloro-2-Fluoroaniline
CAS No.	116369-24-5
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	2-Fluoro-4-bromo-5-chloroaniline; 5-Chloro-4-bromo-2-fluoroaniline; Benzenamine, 4-bromo-5-chloro-2-fluoro-; 4-Bromo-5-chloro-2-fluoro-benzenamine; 2-Fluoro-5-chloro-4-bromoaniline; 4-Br-5-Cl-2-F-aniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-2-Fluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.