Description

2-Fluoro-3-Trifluoromethoxy Aniline is a high-purity fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it a critical intermediate for introducing specific physicochemical properties into target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drugs targeting the central nervous system, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer & Functional Material Modifier: Incorporated into specialty polymers to alter surface properties, increase chemical resistance, and modify refractive indices.
• Organic Synthesis Reagent: A versatile starting material for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to create complex aniline derivatives.

Basic Information

Product Name	2-Fluoro-3-Trifluoromethoxy Aniline
CAS No.	116369-23-4
Molecular Formula	C7H5F4NO
Molecular Weight	195.12 g/mol
Synonyms	2-Fluoro-3-(trifluoromethoxy)aniline; 3-Amino-2-fluoro-1-(trifluoromethoxy)benzene; 2-Fluoro-α,α,α-trifluoro-m-anisidine; 2-Fluoro-3-trifluoromethoxybenzenamine; 2-Fluoro-3-trifluoromethoxyaniline; 2-Fluoro-3-(trifluoromethoxy)benzenamine; 3-Trifluoromethoxy-2-fluoroaniline; AN-116369
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Trifluoromethoxy Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.