Description

Benzaldehyde, 3,4-Dihydroxy-5-(Trifluoromethyl)- (9Ci) is a specialized trifluoromethylated benzaldehyde derivative that serves as a high-value synthetic intermediate. This compound is particularly significant for introducing the trifluoromethyl group, a key moiety known to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group can improve activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Potential monomer or additive for synthesizing advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	Benzaldehyde, 3,4-Dihydroxy-5-(Trifluoromethyl)- (9Ci)
CAS No.	116314-64-8
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	3,4-Dihydroxy-5-(trifluoromethyl)benzaldehyde; 5-(Trifluoromethyl)protocatechualdehyde; 3,4-Dihydroxy-5-trifluoromethylbenzaldehyde; Protocatechualdehyde, 5-trifluoromethyl-; 5-Trifluoromethyl-3,4-dihydroxybenzaldehyde; Benzaldehyde, 3,4-dihydroxy-5-(trifluoromethyl)-; 116314-64-8
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 3,4-Dihydroxy-5-(Trifluoromethyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases. Due to its light-sensitive nature, handling should be performed under subdued light or in amber glass containers when possible.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.