Description

[Leu13]-Motilin Porcine is a synthetic peptide analog of the gastrointestinal hormone motilin, specifically modified at the 13th position with a leucine residue. This modification is critical for studying structure-activity relationships and receptor binding specificity in gastrointestinal motility research. It is an essential biochemical tool for pharmaceutical R&D, academic research, and diagnostic applications focused on digestive system disorders.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active agent in preclinical studies targeting gastrointestinal motility disorders.
• Biochemical Assay Development: Serves as a key ligand in receptor binding assays (RBA) and functional assays to characterize motilin receptor (MTLR) activity.
• Academic & Clinical Research: Fundamental tool for investigating the physiological and pathophysiological roles of motilin in gastric emptying and intestinal motility.
• Peptide Chemistry Studies: Used as a model compound for studying peptide stability, modification effects, and structure-activity relationships (SAR).
• Diagnostic Kit Manufacturing: Potential use as a calibrated antigen or standard in the development of immunoassays for gastrointestinal hormone analysis.

Basic Information

Product Name	[Leu13]-Motilin Porcine
CAS No.	116283-54-6
Molecular Formula	C206H340N60O58S
Molecular Weight	4699.4 g/mol
Synonyms	Leu13-Motilin; Motilin (porcine) [Leu13]-isomer; [Leu(13)]motilin; Porcine Motilin Leu13 analog; Motilin-related peptide; MTLP; Gastrointestinal peptide analog
EINECS	Contact for details

Quality Control

Our [Leu13]-Motilin Porcine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards and support regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.