Description

8-(Pyrimidin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is a sophisticated heterocyclic building block featuring a spirocyclic structure fused with a pyrimidine ring. This compound is of significant value in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures with specific biological activities.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its unique heterocyclic scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a sophisticated ligand in organometallic chemistry for catalysis or as a core structure in material science research.
• Chemical Biology Probe: Employed in academic and industrial research to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the pharmaceutical and agrochemical sectors.

Basic Information

Product Name	8-(Pyrimidin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane
CAS No.	116247-91-7
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	8-(2-Pyrimidinyl)-1,4-dioxa-8-azaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(2-pyrimidinyl)-; 8-Pyrimidin-2-yl-1,4-dioxa-8-azaspiro[4.5]decane; 2-(1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)pyrimidine; Spirocyclic Pyrimidine Derivative; Azaspirodecane Pyrimidine Building Block
EINECS	Contact for details

Quality Control

Our 8-(Pyrimidin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.