Description

Histatin 5 CAS NO 115966-68-2 is a naturally occurring antimicrobial peptide (AMP) found in human saliva, known for its potent antifungal and antibacterial properties. This compound is of significant interest for its role in innate immunity and its potential as a therapeutic agent or functional additive. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and advanced oral care industries for applications ranging from novel drug discovery to bioactive formulations.

Application

• Antifungal Research & Development: Serves as a key model peptide for studying mechanisms of action against Candida albicans and other pathogenic fungi.
• Pharmaceutical Development: Investigated as a lead compound for developing new antimicrobial and anti-infective therapeutic agents.
• Oral Healthcare Products: Explored as a bioactive ingredient in advanced mouthwashes, toothpastes, and gels for preventing oral candidiasis and promoting gingival health.
• Biomaterial Coatings: Used in research for creating antimicrobial surfaces on medical devices, dental implants, and wound dressings.
• Biochemical & Cell Biology Studies: Employed in research to understand peptide-membrane interactions, cell signaling, and innate immune responses.
• Cosmeceutical Formulations: Potential use in skincare products for its antimicrobial and wound-healing promoting properties.

Basic Information

Product Name	Histatin 5
CAS No.	115966-68-2
Molecular Formula	C164H256N50O45S
Molecular Weight	3036.1 g/mol
Synonyms	Histatin-5; Histatin 5 (human); Salivary Histatin 5; Antimicrobial Peptide Histatin 5; Hst5; P155; DSHAKRHHGYKRKFHEKHHSHRGY; Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr
EINECS	Contact for details

Quality Control

Our Histatin 5 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to rigorous internal quality standards to support your scientific and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.