Description

2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-1-Methyl-,trans- is a high-purity fluorinated pyrimidinone derivative, a key advanced pharmaceutical intermediate (API) and building block in modern synthetic chemistry. Its value lies in its unique molecular structure, which is critical for the development of novel antiviral and anticancer agents, offering researchers precise control over stereochemistry and functional group reactivity. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Antiviral Drug Research: Used in the development of active pharmaceutical ingredients (APIs) targeting viral replication mechanisms.
• Oncology Research: Serves as a precursor for fluorinated pyrimidine-based compounds studied for their antitumor properties.
• Agrochemical Synthesis: An intermediate in creating advanced, high-efficacy crop protection agents with specific biological activity.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for specialized chemical production.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and biochemical pathway analysis.

Basic Information

Product Name	2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-1-Methyl-,trans-
CAS No.	115923-92-7
Molecular Formula	C5H8FN3O2
Molecular Weight	161.13 g/mol
Synonyms	trans-4-Amino-5-fluoro-5,6-dihydro-6-hydroxy-1-methyl-2(1H)-pyrimidinone; 4-Amino-5-fluoro-5,6-dihydro-6-hydroxy-1-methyl-2(1H)-pyrimidinone (trans); 5-Fluoro-4-amino-5,6-dihydro-6-hydroxy-1-methyl-2(1H)-pyrimidinone; 5-Fluoro-4-aminodihydropyrimidinone; Fluorinated Dihydropyrimidinone Intermediate; 115923-92-7; trans-5-Fluoro-4-amino-5,6-dihydro-6-hydroxy-1-methylpyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-1-Methyl-,trans- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.