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2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-1-Methyl-,cis- CAS NO 115923-86-9


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CAS No.:115923-86-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-1-Methyl-,cis- is a high-purity, fluorinated pyrimidinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for its unique structural features that enable the synthesis of complex, biologically active molecules.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and production of antiviral and anticancer drug candidates.
  • Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its fluorinated pyrimidine core.
  • Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and nucleoside analogs.
  • Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies and for probing biological mechanisms.
  • Material Science Precursor: Potential use in the synthesis of specialty chemicals and advanced organic materials.

Basic Information

Product Name 2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-1-Methyl-,cis-
CAS No. 115923-86-9
Molecular Formula C5H8FN3O2
Molecular Weight 161.14 g/mol
Synonyms cis-4-Amino-5-fluoro-5,6-dihydro-6-hydroxy-1-methyl-2(1H)-pyrimidinone; 4-Amino-5-fluoro-5,6-dihydro-6-hydroxy-1-methyl-2(1H)-pyrimidinone (cis-); 5-Fluoro-5,6-dihydro-6-hydroxy-1-methyl-4-amino-2(1H)-pyrimidinone; 4-Amino-5-fluoro-6-hydroxy-1-methyl-5,6-dihydro-2(1H)-pyrimidinone; 115923-86-9; cis-5-Fluoro-6-hydroxy-1-methyl-4-amino-5,6-dihydropyrimidin-2(1H)-one
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Quality Control

Our 2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-1-Methyl-,cis- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity ≥ 99.0% (cis-isomer)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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