Description

α-Conotoxin Si CAS NO 115797-06-3 is a selective peptide neurotoxin derived from the venom of cone snails. This compound is a valuable research tool for studying and characterizing specific subtypes of nicotinic acetylcholine receptors (nAChRs) in neurological research. It is primarily used by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in neuroscience, pain management, and drug discovery programs.

Application

• Neuroscience Research: A critical tool for probing the function and distribution of neuronal nicotinic acetylcholine receptor subtypes.
• Drug Discovery: Used in high-throughput screening assays to identify novel compounds targeting nAChRs for conditions like neuropathic pain.
• Pharmacological Studies: Serves as a selective antagonist to understand receptor-ligand interactions and signaling pathways.
• Academic & Institutional Research: Fundamental research in neurophysiology and cellular communication.
• Biomarker Development: Potential use in developing diagnostic tools for neurological disorders linked to nAChR dysfunction.

Basic Information

Product Name	α-Conotoxin Si
CAS No.	115797-06-3
Molecular Formula	C58H86N18O18S4
Molecular Weight	1395.7 g/mol
Synonyms	α-Conotoxin Si; Conotoxin Si; α-Conotoxin SIA; α-CTx Si; Conus striatus toxin Si; Nicotinic Acetylcholine Receptor Antagonist Si; α-Conotoxin SIA Precursor; SI Conotoxin
EINECS	Contact for details

Quality Control

Our α-Conotoxin Si is produced under stringent conditions to ensure high purity and batch-to-batch consistency, essential for reliable research outcomes. Each lot undergoes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and peptide content are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity	Confirmed by functional assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.