Description

Fmoc-Trp-Odhbt CAS NO 115748-09-9 is a specialized, protected amino acid derivative used in solid-phase peptide synthesis (SPPS). This compound is critical for the efficient and high-fidelity incorporation of tryptophan residues into complex peptide chains. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the automated or manual synthesis of custom peptides.
• Pharmaceutical Research & Development: For the production of peptide-based drug candidates, including hormones, antimicrobial peptides, and targeted therapeutics.
• Bioconjugation and Probe Development: Utilized in the creation of fluorescently labeled or otherwise modified peptides for diagnostic and imaging applications.
• Combinatorial Chemistry Libraries: Serves as a building block in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Academic and Industrial Research: Used in biochemical laboratories for studying protein-protein interactions, enzyme substrates, and receptor ligands.
• Production of Peptide Fragments: For the synthesis of specific peptide sequences used as antigens, standards, or intermediates in larger biomolecules.

Basic Information

Product Name	Fmoc-Trp-Odhbt
CAS No.	115748-09-9
Molecular Formula	C₃₃H₂₉N₃O₆
Molecular Weight	563.60 g/mol
Synonyms	Fmoc-Tryptophan-Odhbt Ester; N-(9-Fluorenylmethoxycarbonyl)-L-tryptophan 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl ester; Fmoc-L-Trp-ODhbt; Fmoc-Trp(1)-ODhbt; 1,2,3-Benzotriazin-4(3H)-one, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan]-, 3-ester; Fmoc-Trp-OBt; Fmoc-Tryptophan benzotriazolyl ester derivative
EINECS	Contact for details

Quality Control

Our Fmoc-Trp-Odhbt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive peptide synthesis applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specific results for assay, chiral purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and performance. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.