Description

Pyrimido[5,4-g]quinazoline-4,6(1H,7H)-dione, 5,10-dihydroxy-2,8-dimethyl- (9Ci) is a complex heterocyclic organic compound belonging to the quinazoline-dione class, serving as a key advanced intermediate in pharmaceutical research and development. Its intricate fused-ring structure makes it a valuable scaffold for synthesizing novel bioactive molecules targeting various therapeutic areas. This high-purity chemical is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of kinase inhibitors and other small-molecule drugs. The compound is supplied with a CAS Number of 115705-72-1.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of potential drug candidates, especially in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Kinase Inhibitor Development: Serves as a precursor in the creation of compounds designed to modulate specific kinase pathways involved in cell signaling.
• Biochemical Tool Compound: Utilized in vitro and in vivo studies to investigate biological mechanisms and validate novel therapeutic targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	Pyrimido[5,4-g]quinazoline-4,6(1H,7H)-dione, 5,10-dihydroxy-2,8-dimethyl- (9Ci)
CAS No.	115705-72-1
Molecular Formula	C₁₃H₁₀N₄O₄
Molecular Weight	286.24 g/mol
Synonyms	5,10-Dihydroxy-2,8-dimethylpyrimido[5,4-g]quinazoline-4,6(1H,7H)-dione; 2,8-Dimethyl-5,10-dihydroxypyrimido[5,4-g]quinazoline-4,6-dione; Pyrimido[5,4-g]quinazoline-4,6-dione, 5,10-dihydroxy-2,8-dimethyl-; 5,10-Dihydroxy-2,8-dimethyl-1H,7H-pyrimido[5,4-g]quinazoline-4,6-dione
EINECS	Contact for details

Quality Control

Our Pyrimido[5,4-g]quinazoline-4,6(1H,7H)-dione, 5,10-dihydroxy-2,8-dimethyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We adhere to relevant quality management standards to support our global clientele in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.