Description

Argipressin, Ala(10)- is a synthetic analogue of the neurohypophysial hormone arginine vasopressin, specifically modified at the tenth amino acid position. This modification is critical for enhancing its receptor selectivity and metabolic stability, making it a valuable research tool and a key intermediate in advanced pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroendocrinology, cardiovascular research, and the development of novel peptide-based therapeutics.

Application

• Pharmacological Research: Used as a selective agonist in studies of vasopressin receptor subtypes (V1a, V1b, V2) to investigate their physiological roles and signaling pathways.
• Drug Discovery & Development: Serves as a critical reference standard and intermediate in the synthesis of novel peptide drugs targeting conditions like diabetes insipidus, septic shock, and bleeding disorders.
• Biochemical Assays: Employed in competitive binding assays and functional studies to evaluate the potency and efficacy of new chemical entities.
• Academic Research: Supports fundamental studies in neuroendocrinology, fluid balance regulation, and cardiovascular function.
• Quality Control: Acts as a high-purity standard for the analysis and validation of vasopressin-related products in pharmaceutical quality control laboratories.

Basic Information

Product Name	Argipressin, Ala(10)-
CAS No.	115699-79-1
Molecular Formula	C46H65N15O12S2
Molecular Weight	1084.2 g/mol
Synonyms	[Ala10]-Argipressin; [Alanine10]-Vasopressin; 1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-8-L-arginine-9-L-alanine-vasopressin; Desmopressin analogue; AVP (1-9) Ala10; Vasopressin, 10-L-alanine-
EINECS	Contact for details

Quality Control

Our Argipressin, Ala(10)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and tests for related substances and residual solvents. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0% (by weight)
Solubility	Soluble in water, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.