Description

Z-Arg(Mtr)-Otbu is a protected derivative of the amino acid L-arginine, specifically designed for use in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers who require high-purity, selectively protected building blocks to construct complex peptide sequences with precision. It is an essential raw material for pharmaceutical R&D, particularly in the development of therapeutic peptides, and is also utilized in biochemical research and proteomics.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key protected arginine derivative for the controlled assembly of peptide chains.
• Pharmaceutical Intermediate: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Employed as a reagent in studies involving protein-protein interactions, enzyme substrates, and signal transduction pathways.
• Proteomics and Bioconjugation: Acts as a building block for creating modified peptides and affinity tags used in mass spectrometry and labeling studies.
• Antibody-Drug Conjugate (ADC) Development: Can be utilized in the synthesis of peptide linkers for targeted cancer therapies.
• Combinatorial Chemistry Libraries: A valuable component for generating diverse peptide libraries for high-throughput screening.

Basic Information

Product Name	Z-Arg(Mtr)-Otbu
CAS No.	115608-60-1
Molecular Formula	C₂₅H₃₃N₅O₇S
Molecular Weight	547.62 g/mol
Synonyms	Nα-Z-Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine tert-butyl ester; Z-Arg(Mtr)-O-tBu; Boc-Arg(Mtr)-OH (common confusion check); Nα-Benzyloxycarbonyl-Nω-(2,3,6-trimethyl-4-methoxybenzenesulfonyl)-L-arginine tert-butyl ester; tert-Butyl N-[(benzyloxy)carbonyl]-N-[imino[[(2,3,6-trimethyl-4-methoxyphenyl)sulfonyl]amino]methyl]-L-ornithinate; Z-L-Arg(Mtr)-OtBu; Protected L-Arginine derivative; Mtr-Arg(Z)-OtBu
EINECS	Contact for details

Quality Control

Our Z-Arg(Mtr)-Otbu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and consistency for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.