Description

R-(-)-Desmethyldeprenyl Hydrochloride is a high-purity, enantiomerically pure chiral compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and study of selective monoamine oxidase (MAO) inhibitors and other neuroactive agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on central nervous system (CNS) therapeutics and neuropharmacology.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel MAO-B inhibitors and other neuroprotective drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing and regulatory submissions.
• Biochemical Research: Employed in enzymatic studies to investigate the mechanism and selectivity of monoamine oxidase inhibition.
• Neuropharmacology Studies: Utilized in preclinical research to model and study neurodegenerative pathways and potential therapeutic interventions.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	R-(-)-Desmethyldeprenyl Hydrochloride
CAS No.	115586-38-4
Molecular Formula	C12H17N•HCl
Molecular Weight	203.73 g/mol
Synonyms	(R)-(-)-Desmethyldeprenyl HCl; (R)-N-((1S)-1-Methyl-2-phenylethyl)prop-2-yn-1-amine Hydrochloride; (R)-(-)-N-Desmethylselegiline Hydrochloride; (R)-2-Propyn-1-amine, N-[(1S)-1-methyl-2-phenylethyl]-, hydrochloride; R-(-)-N-Desmethyl-Deprenyl Hydrochloride; (R)-(-)-N-Desmethyldeprenyl Hydrochloride; (R)-N-Desmethylselegiline HCl
EINECS	Contact for details

Quality Control

Our R-(-)-Desmethyldeprenyl Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) providing full specifications and test results is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.