Description

Cobra Cytotoxin Iii CAS NO 115537-67-2 is a potent, three-finger toxin (3FTx) isolated from cobra venom, characterized by its specific cytolytic activity. This compound is a critical research tool for studying ion channel function, cell membrane interactions, and the mechanisms of neurotoxicity and cytotoxicity. It is primarily utilized by pharmaceutical researchers, toxicologists, and academic institutions engaged in neuroscience, pharmacology, and antivenom development.

Application

• Neuroscience Research: Used as a selective probe to study nicotinic acetylcholine receptors (nAChRs) and other ion channels in neuronal cells.
• Pharmacology & Drug Discovery: Serves as a lead compound or model for developing novel therapeutics targeting ion channels and for antivenom research.
• Cell Biology Studies: Employed to investigate mechanisms of cytotoxicity, pore-formation in cell membranes, and programmed cell death (apoptosis).
• Toxicology & Venom Research: Essential for understanding the pathophysiological effects of snake envenomation and for characterizing venom components.
• Biochemical Assay Development: Acts as a standard or reagent in developing high-throughput screening assays for channel activity or toxin neutralization.
• Academic & Institutional Research: Fundamental tool for graduate and post-doctoral research in biochemistry, molecular biology, and toxicology.

Basic Information

Product Name	Cobra Cytotoxin Iii
CAS No.	115537-67-2
Molecular Formula	Contact for details
Molecular Weight	~7 kDa (Approximate, protein)
Synonyms	Cytotoxin III; Cobra Cytotoxin 3; CTX III; Three-Finger Toxin III; Cardiotoxin III; Naja naja atra Cytotoxin III; Venom Cytotoxin; Short Neurotoxin Homolog; Lytic peptide; Membrane-active peptide
EINECS	Contact for details

Quality Control

Our Cobra Cytotoxin Iii is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot is characterized using advanced analytical techniques including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, biological activity (where applicable), and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into working portions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (UV)	≥ 90%
Biological Activity	Assayed (Contact for details)
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.