Description

Alloc-Ala-Oh Dicyclohexylamine Salt is a protected amino acid derivative, specifically the dicyclohexylamine (DCHA) salt of N-Alloc-L-alanine. This compound is a critical building block in modern solid-phase peptide synthesis (SPPS), offering a strategic balance of stability and selective deprotection. It is essential for researchers and manufacturers requiring high-purity, reliable intermediates for the production of complex peptides, APIs, and bioactive molecules. This product is primarily utilized in pharmaceutical R&D, bioconjugation, and the synthesis of peptide-based therapeutics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected alanine derivative for the controlled, sequential assembly of peptide chains.
• Pharmaceutical Intermediate: A key raw material in the synthesis of peptide active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation Chemistry: Used to introduce alanine residues with orthogonal protecting groups for site-specific labeling or modification of biomolecules.
• Combinatorial Chemistry: A valuable building block for generating diverse peptide libraries for drug discovery and screening.
• Research & Development: Employed in academic and industrial labs for methodological development in organic and medicinal chemistry.
• Custom Peptide Production: Serves as a high-purity starting material for contract manufacturing organizations (CMOs) producing peptides at various scales.

Basic Information

Product Name	Alloc-Ala-Oh Dicyclohexylamine Salt
CAS No.	115491-98-0
Molecular Formula	C20H36N2O4
Molecular Weight	368.52 g/mol
Synonyms	N-Alloc-L-alanine dicyclohexylamine salt; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid dicyclohexylamine salt; Fmoc-Ala-OH·DCHA; N-α-Fmoc-L-alanine dicyclohexylammonium salt; N-(9-Fluorenylmethoxycarbonyl)-L-alanine dicyclohexylamine salt; Fmoc-L-alanine DCHA salt; Fmoc-Alanine DCHA; Fmoc-Ala-OH DCHA salt
EINECS	Contact for details

Quality Control

Our Alloc-Ala-Oh Dicyclohexylamine Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D = Specific range provided on COA
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.