Description

32A-Glycine-Calcitonin (Salmon) is a synthetic peptide analog of the calcitonin hormone, specifically the salmon calcitonin variant modified with a glycine residue. This compound is valued for its potent biological activity and high specificity in modulating calcium metabolism and bone resorption. It is primarily utilized by pharmaceutical research and development teams, as well as manufacturers in the biotech sector, for the development of therapeutic agents targeting osteoporosis, Paget's disease, and hypercalcemia.

Application

• Pharmaceutical Active Ingredient (API): Core component in injectable formulations for the treatment of bone disorders.
• Biomedical Research: Used as a critical reference standard and tool compound in studies of calcium homeostasis and osteoclast activity.
• Preclinical Development: Essential for efficacy and pharmacokinetic studies in animal models for metabolic bone diseases.
• Analytical Standard: Serves as a high-purity calibrant in quality control laboratories for HPLC, MS, and peptide mapping.
• Peptide Chemistry Studies: Used in structure-activity relationship (SAR) studies to develop novel calcitonin analogs with improved stability or potency.

Basic Information

Product Name	32A-Glycine-Calcitonin (Salmon)
CAS No.	115472-96-3
Molecular Formula	C₁₄₈H₂₄₄N₄₄O₄₇S₂
Molecular Weight	~3431.9 g/mol
Synonyms	Glycine-Salmon Calcitonin; [Gly¹]-sCT; Calcitonin (salmon), 1-glycine-; Salmon Calcitonin Glycine Analog; 1-Glycine-calcitonin (salmon); H-Gly-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH₂ (Disulfide bridge: Cys¹-Cys⁷)
EINECS	Contact for details

Quality Control

Our 32A-Glycine-Calcitonin (Salmon) is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, and biological activity, meeting the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing results for assay, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccant after each use to maintain stability. For long-term storage, keep lyophilized powder under these conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	≤ 15.0%
Biological Activity	Conforms (by in vitro assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.