Description

Vip (3-28) (Human, Bovine, Porcine, Rat) is a bioactive peptide fragment derived from the vasoactive intestinal polypeptide. This compound is a critical research tool for studying neuroendocrine signaling, immune modulation, and gastrointestinal physiology across multiple species. It is essential for pharmaceutical R&D, academic research, and diagnostic development. Researchers and manufacturers rely on this high-purity peptide for its specificity in receptor binding studies and as a reference standard.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of VIP receptor (VPAC1, VPAC2) signaling pathways.
• Drug Discovery: Serves as a lead compound or pharmacological tool for developing therapeutics targeting inflammatory diseases, neurological disorders, and metabolic conditions.
• Immunology Studies: Applied in research on cytokine modulation, T-cell differentiation, and anti-inflammatory responses due to VIP's immunoregulatory functions.
• Physiological Assays: Utilized in in vitro and ex vivo models to investigate smooth muscle relaxation, vasodilation, and secretory processes.
• Diagnostic Development: Acts as a key antigen or calibrator in the development of immunoassays (ELISA, RIA) for detecting VIP-related biomarkers.
• Cross-Species Comparative Studies: Enables comparative pharmacological analysis between human, bovine, porcine, and rat models, supporting translational research.

Basic Information

Product Name	Vip (3-28) (Human, Bovine, Porcine, Rat)
CAS No.	115444-33-2
Molecular Formula	C136H220N40O39
Molecular Weight	3055.5 g/mol
Synonyms	VIP (3-28); Vasoactive Intestinal Peptide Fragment 3-28; Human VIP (3-28); Porcine VIP (3-28); Bovine VIP (3-28); Rat VIP (3-28); VIP3-28; Vasoactive Intestinal Polypeptide (3-28)
EINECS	Contact for details

Quality Control

Our Vip (3-28) is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized using advanced analytical techniques including HPLC for purity and Mass Spectrometry for identity confirmation. We provide comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and endotoxin levels, supporting research reproducibility and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.