Description

Nle-Sta-Ala-Sta CAS NO 115388-99-3 is a specialized peptide sequence of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and a model substrate for studying protease specificity and designing novel enzyme inhibitors. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, drug discovery, and the development of therapeutic agents targeting specific enzymatic pathways.

Application

• Protease/Enzyme Inhibition Studies: Used as a specific substrate or inhibitor model to investigate the activity and mechanism of various proteolytic enzymes.
• Pharmaceutical R&D: Serves as a key intermediate in the research and development of novel peptide-based therapeutics and diagnostic agents.
• Biochemical Research: Employed in academic and industrial laboratories for studying protein-protein interactions, signal transduction, and metabolic pathways.
• Peptide Library Synthesis: Acts as a component in the construction of combinatorial peptide libraries for high-throughput screening.
• Structure-Activity Relationship (SAR) Studies: Utilized to understand the correlation between peptide structure and biological function for drug optimization.

Basic Information

Product Name	Nle-Sta-Ala-Sta
CAS No.	115388-99-3
Molecular Formula	C33H58N6O7
Molecular Weight	650.85 g/mol
Synonyms	Nle-Sta-Ala-Sta; Nleu-Sta-Ala-Sta; Norleucyl-Sta-Alanyl-Sta; (2S)-2-[[(2S,3S)-3-[[(2S)-2-[[(2S,3S)-3-Amino-2-hydroxy-4-methylpentanoyl]amino]propanoyl]amino]-2-hydroxy-4-methylpentanoyl]amino]-5-amino-5-oxopentanoic Acid; Statine-containing peptide; Protease inhibitor peptide fragment
EINECS	Contact for details

Quality Control

Our Nle-Sta-Ala-Sta is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to cGMP guidelines where applicable to support our clients' preclinical and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.