Description

Cholecystokinin-33 Human Sulfated is a biologically active, sulfated peptide hormone consisting of 33 amino acids, identical to the human form. This high-purity compound is critical for research and development in neurogastroenterology and metabolic studies due to its role in stimulating pancreatic enzyme secretion and gallbladder contraction. It is an essential biochemical tool for pharmaceutical R&D, academic research, and diagnostic applications focusing on digestive and central nervous system functions.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active agent in drug discovery programs targeting gastrointestinal disorders, appetite regulation, and anxiety.
• Academic & Biomedical Research: Serves as a key reagent in physiological studies investigating hormone-receptor interactions, signal transduction pathways, and the brain-gut axis.
• In Vitro Diagnostic (IVD) Development: Employed in the calibration and validation of immunoassay kits designed to measure cholecystokinin levels in clinical samples.
• Metabolic & Obesity Studies: Utilized in research exploring the role of satiety hormones, food intake regulation, and potential therapeutic interventions for metabolic diseases.
• Neuroscience Research: Applied in studies examining the neuromodulatory functions of cholecystokinin in pain perception, memory, and behavior.

Basic Information

Product Name	Cholecystokinin-33 Human Sulfated
CAS No.	115365-94-1
Molecular Formula	C186H286N50O58S3
Molecular Weight	~3918.8 g/mol
Synonyms	CCK-33; CCK33; Cholecystokinin (33-); Cholecystokinin-33, sulfated; CCK (33-); Pancreozymin; CCK-PZ; Sincalide precursor; CCK-33, human; 115365-94-1
EINECS	Contact for details

Quality Control

Our Cholecystokinin-33 Human Sulfated is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with rigorous research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -70°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Assessed by in vitro bioassay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.