Description

2,4(1H,3H)-Pyrimidinedione, 5-(Hydroxyamino)- (9Ci) is a specialized pyrimidine derivative, a key heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique functionalization, combining a pyrimidinedione scaffold with a reactive hydroxyamino group, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical development teams working on nucleoside analogs, enzyme inhibitors, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Biochemical Research: Used as a building block for modifying nucleic acids and studying enzyme-substrate interactions, particularly with enzymes targeting pyrimidine metabolism.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and plant growth regulators that utilize modified heterocyclic cores.
• Organic Synthesis Reagent: Acts as a versatile synthon for introducing the 5-hydroxyaminopyrimidine moiety into more complex molecules for material science and fine chemical applications.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes to investigate biological pathways and protein functions.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione, 5-(Hydroxyamino)- (9Ci)
CAS No.	115154-50-2
Molecular Formula	C4H5N3O3
Molecular Weight	143.10 g/mol
Synonyms	5-Hydroxyaminouracil; 5-(Hydroxyamino)uracil; 5-Hydroxyaminopyrimidine-2,4(1H,3H)-dione; 5-NHOH-Uracil; 5-Hydroxyamino-2,4-dihydroxypyrimidine; 5-Hydroxyaminopyrimidine-2,4-diol; 5-(Hydroxyamino)-2,4(1H,3H)-pyrimidinedione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material of high chemical purity suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Quality is assured through analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere and minimize exposure to air and moisture for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.