Description

Bio-Ahx-Angiotensin II is a synthetic, bioactive peptide analog of the endogenous vasoconstrictor hormone Angiotensin II, modified with an aminohexanoyl (Ahx) linker. This modification enhances its stability and utility in biochemical research and pharmaceutical development. It is a critical tool for researchers in cardiovascular pharmacology, receptor binding studies, and the development of diagnostic assays. The product is supplied as a high-purity lyophilized powder for precise experimental use.

Application

• Biochemical Research: Used as a reference standard and ligand in studies of the renin-angiotensin system (RAS) and AT1/AT2 receptor binding assays.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of cardiovascular drugs and diagnostic kits.
• Cell Signaling Studies: Applied to investigate intracellular signaling pathways, calcium mobilization, and vascular smooth muscle contraction mechanisms.
• In Vitro Diagnostics (IVD): Utilized as a calibrated antigen in immunoassays (e.g., ELISA) for the detection and quantification of angiotensin-related biomarkers.
• Peptide Chemistry: Acts as a building block or model compound for studying peptide stability, conjugation techniques, and structure-activity relationships (SAR).

Basic Information

Product Name	Bio-Ahx-Angiotensin II
CAS No.	115102-72-2
Molecular Formula	C₅₀H₇₁N₁₃O₁₂
Molecular Weight	1030.2 g/mol
Synonyms	Angiotensin II, Ahx-modified; [Ahx]-Angiotensin II; Asp-Arg-Val-Tyr-Ile-His-Pro-Ahx; N-6-Aminohexanoyl-Angiotensin II; Angiotensin II AHA conjugate; Bio-Ahx-Ang II; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Ahx-OH; DRVYIHP-Ahx
EINECS	Contact for details

Quality Control

Our Bio-Ahx-Angiotensin II is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.