Description

4-Amino-5-Bromo-7-(2-Hydroxyethoxymethyl)Pyrrolo(2,3-D)Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel nucleoside analogs and antiviral agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics, particularly for antiviral and oncology applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Development: Serves as a core scaffold for research into treatments targeting viral polymerases and reverse transcriptases.
• Oncology Research: Used in the development of targeted kinase inhibitors and other small-molecule cancer therapeutics.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and proteomics research.
• Fine Chemical Synthesis: A versatile building block for constructing complex, fused heterocyclic systems in medicinal chemistry.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-Amino-5-Bromo-7-(2-Hydroxyethoxymethyl)Pyrrolo(2,3-D)Pyrimidine
CAS No.	115093-88-4
Molecular Formula	C9H11BrN4O2
Molecular Weight	287.12 g/mol
Synonyms	4-Amino-5-bromo-7-(2-hydroxyethoxymethyl)-7H-pyrrolo[2,3-d]pyrimidine; 7-(2-Hydroxyethoxymethyl)-4-amino-5-bromopyrrolo[2,3-d]pyrimidine; 5-Bromo-4-amino-7-(2-hydroxyethoxymethyl)pyrrolo[2,3-d]pyrimidine; ABHPP; Pyrrolo[2,3-d]pyrimidine, 4-amino-5-bromo-7-(2-hydroxyethoxymethyl)-; CAS 115093-88-4
EINECS	Contact for details

Quality Control

Our production of 4-Amino-5-Bromo-7-(2-Hydroxyethoxymethyl)Pyrrolo(2,3-D)Pyrimidine adheres to stringent quality management systems, ensuring batch-to-batch consistency for critical R&D and manufacturing applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects requiring material compliant with ICH guidelines and can provide custom synthesis under cGMP conditions for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Single Impurity (HPLC)	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.