Description

(2,4-Dinitrophenyl)Aminohexanoylangiotensin II is a chemically modified peptide derivative of the potent vasoconstrictor hormone Angiotensin II, designed for advanced biochemical and pharmacological research. This compound matters as a critical tool for studying the renin-angiotensin system (RAS), receptor binding mechanisms, and for developing novel diagnostic assays. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on cardiovascular disease, hypertension research, and peptide-based therapeutic discovery.

Application

• Biochemical Research: Used as a labeled analog or competitor in receptor-ligand binding studies and enzyme inhibition assays related to the renin-angiotensin system.
• Diagnostic Development: Serves as a key antigen or hapten in the development of immunoassays (e.g., ELISA) for detecting Angiotensin II or related peptides.
• Pharmaceutical R&D: Employed as a reference standard or intermediate in the discovery and characterization of novel antihypertensive drugs and RAS modulators.
• Metabolic Pathway Studies: Facilitates research into the metabolic fate and conversion pathways of Angiotensin II and its analogs.
• Affinity Chromatography: Can be immobilized for the purification of specific antibodies or receptors from complex biological mixtures.
• Signal Transduction Research: Aids in elucidating downstream signaling cascades activated by Angiotensin II receptor subtypes (AT1, AT2).

Basic Information

Product Name	(2,4-Dinitrophenyl)Aminohexanoylangiotensin II
CAS No.	115082-70-7
Molecular Formula	C58H84N18O15
Molecular Weight	1249.4 g/mol
Synonyms	Angiotensin II, Nα-(6-[(2,4-Dinitrophenyl)amino]hexanoyl)-; DNP-Ahx-Angiotensin II; (2,4-DNP)Ahx-Ang II; N-ε-(2,4-Dinitrophenyl)-6-aminohexanoyl-Angiotensin II; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe (Nα-DNP-Ahx modified); DNP-Lys(Ahx)-Angiotensin II analog; Labeled Angiotensin II derivative; DNP-conjugated Angiotensin II
EINECS	Contact for details

Quality Control

Every batch of (2,4-Dinitrophenyl)Aminohexanoylangiotensin II is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure high purity and batch-to-batch consistency for research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; partially soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.