Description

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu Acetate Salt is a synthetic peptide sequence, also known as a Bradykinin potentiating peptide (BPP), with significant research and pharmaceutical interest. This compound is valued for its role in modulating the renin-angiotensin system and as a key intermediate in the development of cardiovascular and metabolic research tools. It is primarily required by biotechnology firms, pharmaceutical R&D laboratories, and academic research institutions focused on peptide chemistry, hypertension studies, and drug discovery programs.

Application

• Pharmaceutical Research & Development: As a critical intermediate or reference standard in the synthesis of novel therapeutic peptides targeting cardiovascular diseases.
• Biochemical Assay Development: For use in enzymatic inhibition studies, particularly related to angiotensin-converting enzyme (ACE) activity.
• Academic & Clinical Research: As a tool compound for investigating the physiological pathways of bradykinin and related peptides in vascular biology.
• Peptide Library Synthesis: Serving as a building block or a specific sequence in custom peptide library construction for high-throughput screening.
• Reference Standard: For quality control and analytical method development in peptide manufacturing and characterization.

Basic Information

Product Name	Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu Acetate Salt
CAS No.	115035-45-5
Molecular Formula	C44H66N14O11 • xC2H4O2
Molecular Weight	999.1 g/mol (free base)
Synonyms	Bradykinin Potentiating Peptide (BPP); Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu; RPPGFSPL acetate; H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu-OH acetate; ACE Inhibitory Peptide; Peptide BPP; Nonapeptide BPP; CAS 115035-45-5
EINECS	Contact for details

Quality Control

Our Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu Acetate Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and tests for residual solvents and acetates. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This hygroscopic (moisture-sensitive) material should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. Keep container tightly sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	5.0% - 12.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.