Description

R(-)-Norapomorphine Hydrobromide is a high-purity, enantiomerically pure salt form of the aporphine alkaloid derivative, norapomorphine. This compound is a critical reference standard and research chemical in neuropharmacology, primarily due to its potent and selective activity as a dopamine receptor agonist. It is essential for pharmaceutical R&D, academic research, and analytical laboratories focused on studying Parkinson's disease, schizophrenia, and other dopamine-related neurological pathways.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and impurity profiling of active pharmaceutical ingredients (APIs) in quality control and method development.
• Neuroscience Research: A key tool for in vitro and in vivo studies investigating dopamine D1 and D2 receptor signaling, neuroprotection, and behavioral pharmacology.
• Drug Discovery & Development: Serves as a lead compound or biochemical probe for developing novel therapeutics targeting central nervous system (CNS) disorders.
• Analytical Chemistry: Employed as a calibration standard in advanced chromatographic (HPLC, LC-MS) and spectroscopic analyses.
• Academic & Clinical Studies: Facilitates fundamental research into the mechanisms of addiction, movement disorders, and cognitive function.

Basic Information

Product Name	R(-)-Norapomorphine Hydrobromide
CAS No.	115017-61-3
Molecular Formula	C16H17NO2 • HBr
Molecular Weight	344.23 g/mol
Synonyms	(-)-Norapomorphine HBr; (R)-(-)-Norapomorphine Hydrobromide; R-(-)-Norapomorphine HBr; 6aβ-Aporphine-10,11-diol Hydrobromide; (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol Hydrobromide; Norapomorphine HBr; R(-)-N-norapomorphine Hydrobromide
EINECS	Contact for details

Quality Control

Our R(-)-Norapomorphine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific pharmacopeial or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.