Description

5-Chloro-2-Fluoro-4-(Trifluoromethyl)Aniline is a high-value fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides exceptional electronic and steric properties for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups contribute to efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic diamines and other components in electronic display materials, contributing to improved performance and stability.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, where its aromatic amine functionality allows for cross-linking and modification of material properties.
• Dye & Pigment Manufacturing: Acts as a starting material for synthesizing novel, light-fast fluorinated dyes and organic pigments.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in organofluorine chemistry.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-(Trifluoromethyl)Aniline
CAS No.	114973-23-8
Molecular Formula	C7H4ClF4N
Molecular Weight	213.56 g/mol
Synonyms	4-Amino-2-chloro-5-fluorobenzotrifluoride; 2-Chloro-5-fluoro-4-(trifluoromethyl)aniline; 5-Chloro-2-fluoro-α,α,α-trifluoro-p-toluidine; 2-Chloro-α,α,α,5-tetrafluoro-p-toluidine; Benzenamine, 5-chloro-2-fluoro-4-(trifluoromethyl)-; 5-Chloro-2-fluoro-4-trifluoromethylaniline; 4-(Trifluoromethyl)-5-chloro-2-fluoroaniline
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-2-Fluoro-4-(Trifluoromethyl)Aniline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with relevant regulatory frameworks for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.