Description

4-Amino-2,5-Difluorobenzotrifluoride is a high-value, multi-functional aromatic amine intermediate distinguished by its unique trifluoromethyl and fluorine substituents. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, leveraging the fluorine atoms for improved biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorine-containing liquid crystals used in display technologies.
• Polymer & Dye Industry: Intermediate for producing specialty polymers, dyes, and pigments where thermal and chemical stability are required.
• Organic Synthesis & R&D: A versatile reagent for introducing the 2,5-difluoro-4-aminophenyl motif into more complex molecular architectures in research settings.

Basic Information

Product Name	4-Amino-2,5-Difluorobenzotrifluoride
CAS No.	114973-22-7
Molecular Formula	C7H4F5N
Molecular Weight	197.11 g/mol
Synonyms	2,5-Difluoro-4-(trifluoromethyl)aniline; 4-Amino-2,5-difluoro-α,α,α-trifluorotoluene; 2,5-Difluoro-α,α,α-trifluoro-p-toluidine; 4-(Trifluoromethyl)-2,5-difluoroaniline; 2,5-Difluoro-4-aminobenzotrifluoride; 4-Amino-2,5-bis(fluoranyl)-1-(trifluoromethyl)benzene (IUPAC); Benzenamine, 2,5-difluoro-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Amino-2,5-Difluorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.